Ronaldo departed for Juventus in July and left a gaping hole that Madrid have struggled to fill with a five-match winless run in all competitions heaping pressure on coach Julen Lopetegui.
Saturday’s 2-1 home defeat to Levante prompted talk Lopetegui could be dismissed prior to Tuesday’s Champions League clash with Viktoria Plzen but the former Spain coach carried out his media duties as normal on Monday and must hope a resounding midweek win will give him the chance to lead the side in Sunday’s first Clasico of the season against Barcelona.
Isco offered his backing to Lopetegui and swatted aside questions about how the team were seemingly failing to cope following Ronaldo’s exit.
The Spain international said: “We’ve been talking about this all season.
“There’s no point in talking about someone who isn’t here.
“I miss [Gareth] Bale and [Dani] Carvajal when they’re not available. We have the solutions in the squad to score goals.
“We can’t cry about someone who didn’t want to be here.”