Five Of The Rarest Medical Conditions Ever Diagnosed

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Medical practitioners have seen a lot over the course of their practice and some of the conditions are so rare that they maybe found in one in a million people.

Rat Bite Fever
This medical condition is usually characterised by a rash on the bottom of the feet, accompanied with headaches and joint pains. Doctors will usually ask weird questions before determining if a patient has rat bite fever.

This condition will usually occur in people that experienced a eat bite and it is essential to get to a hospital immediately you experience this.

Primary Amoebic Meningoencephalitis (PAM)
This condition is usually characterised with persistent headaches, and no past medical history of anything similar or really at all about her that stood out as relevant. if not quickly diagnosed, rapid deterioration may occur, with high fevers and periodic losses of consciousness.

A cerebrospinal fluid (CSF) culture is usually used in diagnosis and will usually be positive for Naegleria fowleri (aka N. fowleri), the pathogen responsible for Primary Amoebic Meningoencephalitis (PAM).

This condition is the incurable brain-eating amoeba that lives in warm stagnant water, and can enter through the cribriform plate at the top of the nose if the patient gets water up there, which may happen at waterparks.

This condition is usually fatal but it can be managed by lowering body temperature of the patient to below what N. fowleri can usually survive. Unfortunately, most people can’t survive it either.


Creutzfeldt-Jakob Disease (CJD)
Characterised with lower leg swelling, confusion, high body temperature and stiffness, CJD is usually confused with meningitis.

It’s a one in a million (literally) diagnosis, and most doctors will hardly ever come across it.

Cat’s Cry Syndrome
anyone affected with this condition will usually cry all day long and have a cry that is similar to that of a cat. Cri-du-chat syndrome or cat’s cry syndrome is very very rare and can be difficult for medical practitioners to identify. Diagnosis will usually involve genetic testing.

Wegner’s Syndrome
Wegner’s Syndrome may have a patient coughing up blood intermittently and is more often than not confused with tuberculosis but all tests to the latter will usually be negative.

However, a urine test will show lots of blood, despite the patient having good renal function and the condition is mostly known as granulomatosis with polyangiitis (Wegner’s).



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