Guus Hiddink has opted to relegate Oscar to the bench, as he plays Fabregas in a more advanced role.
Hiddink has now returned underperforming midfielder, Matic to the squad, to partner Mikel in midfield.
For Everton, Lukaku leads the attack against his former club.
CHELSEA: Courtois; Ivanovic, Zouma, Terry (c), Azpilicueta; Mikel, Matic; Willian, Fabregas, Pedro; Diego Costa
SUBS: Begovic, Baba, Cahill, Loftus-Cheek, Kenedy, Oscar, Remy
EVERTON: Howard, Oviedo, Baines, Stones, Jagielka, Besic, Barry, Lennon, Barkley, Mirallas, Lukaku
SUBS: Robles, Kone, Cleverley, Deulofeu, Osman, Pienaar, Funes-Mori