They were plagued with injuries last season and manager, Louis van Gaal has blamed the training season he implemented.
Van Gaal’s men are now back in training after a UCL 1-1 draw with CSKA Moscow, and are preparing for the clash against City.
In his first campaign at Old Trafford, Van Gaal’s coaching methods came under fire with 10 of his first-team players on the sidelines with injury at one time.
“That was my fault. I was training them harder but they were not used to training like that,” said Van Gaal .
“Because I am convinced you have to train now they are used to that step. I also let go players because of that and I bought new players. I think they are more used to my training sessions. You can see that with the new players. You can see which players are always injured.
“In my career I never had injuries like that [last year]. I have always preferred small squads. I think I have the smallest squad in the Premier League. You always have to train but with structure and not too hard.”
One man Van Gaal is hoping stays healthy is Chris Smalling who has been tipped to replace Wayne Rooney as the club’s captain by his manager.