Arsene Wenger has opted to start Walcott ahead of regular striker Giroud against Newcastle.
Giroud has eight goals in six fixtures against Newcastle, but couldn’t find the net against Liverpool. Ozil joins the Frenchman on the bench due to a knee injury.
Newcastle welcome back defender, Janmaat who picked up a red card and a game suspension in their 2-0 defeat to Swansea.
Newcastle: Krul, Janmaat, Mbemba, Coloccini, Haidara, Anita, Colback, Sissoko, Wijnauldum, Thauvin, Mitrovic
Subs: Darlow, Cisse, De Jong, Obertan, Perez, Tiote, Taylor
Arsenal: Cech, Bellerin, Koscielny, Gabriel, Monreal, Coquelin, Cazorla, Oxlade-Chamberlain, Ramsey, Sanchez, Walcott
Subs: Ospina, Debuchy, Gibbs, Arteta, Giroud, Chambers, Campbell