Baby Born With HIV/AIDs Cured; Researchers Hopeful Of More Success

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A Mississippi baby born with the AIDS virus appears to have been cured after being treated with an aggressive regimen of drugs just after her birth 2½ years ago, an unusual case that could trigger changes in care for hundreds of thousands of babies born globally each year with HIV.

The findings, reported Sunday by researchers, mark only the second documented case of a patient being cured of infection with the human immune-deficiency virus. The first, an adult man known as the Berlin patient, was cured as a result of a 2007 bone-marrow transplant.

The new case was discovered after the baby girl’s mother stopped treatment on her, and doctors realized that the virus was undetectable even without drugs, which HIV patients normally must take for the rest of their lives.

Researchers cautioned that the report on the baby girl involves just one patient, and the findings appear to have little immediate relevance to people who contract HIV as adults or adolescents and are almost always diagnosed and treated long after their initial infection. But if further study confirms that very early treatment can cure HIV-infected newborns, it could spur widespread use of such an aggressive regimen in babies born with HIV, nearly all of them in low- and middle-income countries.

World Health Organization guidelines now call for treating infants born to an HIV-infected mother with a modest daily dose of antiretroviral treatment for four to six weeks—or until testing determines the baby’s own HIV status. If the baby tests positive, a more aggressive treatment is begun.

But WHO doesn’t address use of a more intense medication approach right after birth, in part because few studies have examined the issue. In addition, it is difficult to determine with certainty that early whether a baby is HIV-positive, and overtreatment would risk wasting scarce medications that offer a better chance of helping other patients.

In this case, researchers believe that a doctor’s decision to start an aggressive antiretroviral treatment within 31 hours of the infant’s birth led to the cure. They theorize that the drugs prevented the formation of so-called viral reservoirs that harbor the virus. These reservoirs have been the key stumbling block to a cure because even though AIDS drugs stop HIV from replicating, the virus lurks in the reservoirs, ready to come surging back when treatment is stopped.

In this case, “the child got therapy and then went off therapy, and now there’s no detectable virus,” said Deborah Persaud, a pediatrician and AIDS researcher at Johns Hopkins Children’s Center in Baltimore and lead author of a study reporting the cure. “That’s really unheard of. If people go off therapy, most of them rebound…within a few weeks.”

She described the findings at a news conference Sunday in advance of their presentation Monday at the annual Conference on Retroviruses and Opportunistic Infections in Atlanta.

“This is a very important proof of concept” said Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases, an arm of the National Institutes of Health. Further research is required “to see if you can generalize this to children who are born into situations where their risk of infection is very high.”

The chance an infected pregnant woman will transmit the virus to her baby during gestation, birth or breast-feeding ranges from 15% to 45%, according to WHO. But treatment with antiretroviral therapy during pregnancy and especially around the time of birth cuts the risk of mother-to-child transmission to below 2%. Still, estimates are that between 300,000 and 400,000 infants are born globally each year with the infection, about 90% of them in resource-poor countries in sub-Saharan Africa.

In the U.S., high compliance with prenatal care and routine HIV testing during pregnancy has all but eliminated HIV-positive newborns. From a peak of 1,650 cases in 1991, the U.S. Centers for Disease Control and Prevention says the number is now down to fewer than 200 a year.

In 2010, the number was 174. One of them, born in a rural Mississippi hospital that fall, is now the first case of a child considered cured of the disease.

The baby was born to a mother who hadn’t had prenatal care and didn’t know her HIV status. A rapid HIV test after the birth revealed that she was infected, prompting doctors to transfer the baby to University of Mississippi Medical Center more than 100 miles away.

There, Hannah Gay, a pediatrician and infectious-disease expert, ordered an HIV test for the infant. She didn’t wait for the result. Figuring this was an especially high-risk case, Dr. Gay started the baby on three standard antiretroviral drugs at higher, treatment-level doses. A few days later, the test came back positive, she said, and she kept the infant on the treatment-level doses.

Over the next few weeks, the baby’s viral levels gradually declined, and by day 29, HIV couldn’t be detected with standard testing. That remained the case for more than a year.

“I saw her once a month; her viral load was undetectable, and her immune system was healthy—what we expect with a baby taking the medicines regularly,” Dr. Gay said.

But at about 18 months, for reasons that aren’t clear, the mother stopped bringing the baby in for the checks. Dr. Gay summoned health-department and child-protection workers, who found her last August, and she returned to the clinic. The baby had been off therapy for at least five months, Dr. Gay said.

Before resuming treatment, Dr. Gay ordered a test to make sure the baby’s virus hadn’t developed resistance to any of the drugs. To her astonishment, technicians couldn’t find any virus to test.

At first, Dr. Gay worried that she had been treating an uninfected baby for more than a year. But a quick check of her records verified that five different tests had detected the virus in the days and weeks following her birth.

When she was convinced last August, she called a longtime friend and colleague, Katherine Luzuriaga, a researcher at University of Massachusetts Medical School. Dr. Luzuriaga had been working with Dr. Persaud on a study of a group of teenagers who had been born with the virus and treated since infancy and who now had no evidence of virus that could replicate. The pair had set up a network of labs to study whether they could consider taking the teenagers off the drugs.

With that lab network, established with a grant from the Foundation for AIDS Research, a New York-based philanthropy, samples from the baby have been subjected to a variety of the most advanced tests to detect and monitor the AIDS virus.

While the tests have detected an occasional “signal” of the virus, the various analyses from several labs using different techniques “confirms to us that this is a case of ‘functional cure,’ meaning that the virus hasn’t rebounded and that…we can’t detect virus activity in this child,” Dr. Persaud said. The work also was supported by the NIH.

Wana

Wana

Quo non Ascendam. Writer.
E-mail: wana@360nobs.com

19 comments

  1. M MRS LINDA DUBLY = Hello” thankgod for the wonderful healing spell power which Dr Olorun Oduduwa render to my life which oracle support, i was been diagnosed with HIV-AIDS over 7years now which has lead me to unployment and loosing my relationship with my fiance after he heard that i am suffering from the VIRUS, i tried begging him to allow me stays with him, but he still insist on letting me out of his home, until a friend of mine on facebook from SOUTH AFRICA told me more about Dr ojuku the great healer, that he is going to help restore and healed my diseased with his powerful healing spell, she send me of Dr ojuku email address and i quickly contacted him, and he replied to after 30mins of my message that my disease is a little and minor disease, that he will solved the disease immediately only if i can accept all he requested from, i told him yes, because truly i know that ” HIV-AIDS IS A WICKED AND DEADLY DISEASE I EVER KNOWS “. so i did all he want from me and suprisingly on friday last week DR OJUK called me that my problems is solvesd that i should hurry up to the hospital for a checkup, which i truly really did, i comfirm from my doctor that i am now HIV-NEGATIVE AND NOT LONG +, I jump up and was crying heavily because truly the disease drive alot of things away from my life, my friends, my cousin, my fiance and relatives, but now since i was comfirm NEGATIVE- my lost friends and fiance has been back to me begging for forgiveness, i have forgiven them and now we are now best of friend. again i will say to Dr Oojuku that he is blessed and may the almighty God which i serve raise him and his family to the higher level in life. Thank and god bless. Please email DR ojuku for healing and solution now at = drojukuspellhome@g mail.com

  2. Hello my Name is Samara I want to thank Dr okpoko for helping me, because ever since
    September 2006, I have been HIV positive it was confirm by my doctor that I’m hiv positive. So one day as I was browsing through the internet I saw a testimony on how this great man called Dr Okpoko help a girl called manilla cure her HIV AIDS, this was really terrible, as i rush to quickly contact him for a cure, as i contact him and he told me not to worry that he will help me, that I should give him two days to cast the spell with his oracle {spirits} to tell him what to do, he later told me on what items and materials i am to buy over here in my country, i purchase them, so after two days he call Me to go for a test and I go for the test and I was now hiv negative I’m very happy now that I’m hiv negative I’m thankful to dr Okpoko for helping me his email adderss : dr.okpokospellhome@gmail.com

  3. DR ukpoyan is the only Dr who could ever get my HIV-AIDS cured with his healing spell, i have tried almost everything but i could’nt find any solution on my disease, despite all these happening to me, i always spend a lot to buy a HIV drugs from hospital and taking some several medications but no relieve, until one day i was just browsing on the internet when i come across a great post of !Michelle! who truly said that she was been diagnose with HIV and was healed that very week through the help of these great powerful healing spell doctor, sometime i really wonder why people called him Papa ukpoyan, i never knew it was all because of the great and perfect work that he has been doing that is causing all this. so i quickly contacted him, and he ask me some few questions and he said a thing i will never forget that anyone who contacted him is ! always getting his or her healing in just 6 hours after doing all he ask you, so i was amazed all the time i heard that from him, so i did all things only to see that at the very day which he said i will be healed, all the strength that has left me before rush back and i becomes very strong and healthy, this disease almost kills my life all because of me, so i will to hospital to give the final test to the disease and the doctor said i am HIV negative, i am very amazed and happy about the healing Dr ukpoyan gave to me from the ancient part of Africa, you can email him now for your own healing too at: dr.ukpoyanspellhome@hotmail.com

  4. I have been suffering hardship from HIV/AIDS since 7yrs now, and i happen to have 2 kids for my husband, and now we cannot proceed to have another kids all because of my disease and now i have do all what a human like i and my husband can do just to get my disease healed, i have went to several places to seek for help not even one person could ever help, until i melt a comment on the daily news paper that was commented by Desmond about how this powerful traditional doctor help him get cured of the disease (HIV-AIDS) ” my fellow beloved” i firstly taught having a help from a spiritual traditional healer was a wrong idea, but i think of these, will i continue to stress on these disease all day when i have someone to help me save my life?” so i gather all my faiths and put in all interest to contact him through his Email address at dr.okpokospellhome@gmail.cok, so after i have mailed him of helping get my disease cured, he respond to me fast as possible that i should not be afraid, that he is a truthful and powerful doctor which i firstly claimed him to be. So after all set has been done, he promise me that i will be healed but on a condition that i provide him some items and obeyed all his oracle said. I did all by accepting his oracles fact and only to see that after some weeks of taking his herbal medicine i notice some changes in my body system and i went for check up the day he ask me to go for check up to confirm if the sickness was still there,to my greatest surprise i could not find any sickness in my body i was first shocked and later arise to be the happiest woman on earth after i have concluded my final test on the hospital by my doctor that i am now HIV- Negative. My papers for check are with me and now i am happy and glad for his miraculous help and power.
    With these i must tell everyone who might seek for any help, either for HIV cure or much more to contact him now at these following email now, Email: dr,okpokospellhome@gmail.com
    ” sir thank you so much for your immediate cure of my disease, i must say a big thanks for curing my disease, i owe you in return. Thanks and be blessed sir.
    FAITH MITCHELL

  5. I was diagnosed with the deadly disease for over five years until I met the great spell caster who is DR.OKORUNDO who helped me in curing my disease, I was searching through the internet when I saw a testimony on how a great spell caster helped someone in curing his HIV disease, I taught it was a lie until I saw many testimonies on the same man helping them getting rid of their diseases, quickly I emailed him quickly told him of my problems he told me to buy some items which I did, after getting the items he told me that he will be using 45 minutes to cast the spell, I believed him coz I saw many testimonies on how he uses 45 minutes to cast a curing spell, truly he finished doing it and asked me to go for a medical checkup, I went to the hospital and do the check up, brothers and sisters I couldn’t believe what I saw on the result, I rushed down to another hospital it was the same, hmmm, am very grateful for what DR.OKORUNDO did in my life. I will as well tell you people out there living with the same disease or any other deadly disease like CANCER, LIVER PROBLEMS, CHEST PAIN, ALL TYPES OF DEADLY DISEASE you can email him on DR.OKORUNDO@HOTMAIL.COM or call +2347067167955. he is waiting to help you.

  6. Do you know that there is a great spell caster who can cure any deadly
    disease. Like Cancer, Hiv, syphilis, e.t.c. Well my main reason why i
    am writing this right now is to inform the whole world about the great
    deeds, Dr. okorom did for me. I was diagnosed of this deadly disease
    in the year 2000 ever since then i was taking my medications, until i
    met the great spell caster, though i never believed in spell. I saw
    many testimonies on how a great spell caster cured thier deadly
    diseases. I contacted him through his phone number. I called him, he
    asked me to send him my email, which i did. He gave me a form to fill,
    I filled it and send it back to him. He told me that his god’s
    required some items in which he will use in casting a curing spell on
    me. I don’t know where to find the items he required. He told me that
    the only alternative is for of to send him the money, then he can help
    me to purchase the items from the items sellers. I promised myself to
    do anything to get cured. I sent him the money. He bought the items
    and casted a curing spell on me. Two day later he asked me to go for
    check-up, when i did the check-up i was tested HIV Negative. If you
    passing through hardship and you need a way out, kindly contact him
    via his email on dr.okoromspellhome@live.com or call his number on
    +2348127147869

  7. hello, my name is Jose from united kingdom, i want to share this wonderful testimony to you guy in case you are in this same problem. i was suffering from HIV/AIDS for 1 year and 9 months until i meant Doctor Aluta who counseled me and told me he could cure me, i never believed him, i thought that there was never a cure for my deadly ailment. Doctor Aluta told me that his herbs could cure me, and then i decided to give it a try, he told me that once i start taking it, that it will only take me some days to be cured, and i believed him, after he gave me the medicine, behold i took it and i was cured in just 3 days, i even went for a test to confirm it and now i am very happy to tell you that i am now HIV/AIDS negative and i am also happy that i will not be celebrating this Christmas as a HIV/AIDS patient, so help me say a very big thank you to Doctor Aluta and God for saving me from the hands of the deadly ailment, if you also need help in this type of issues you are very free to contact him today through his private email: alutaspelltemple@hotmail.com or call him on his mobile number : +2348077526430.

  8. Hello my name is faith mitchell I want to give a testimony about my HIV virus that was cured by a great spell caster. Since last 4 months I have being a HIV AID patient. I never think I live long again and am so grateful about him DR.Okpoko who help me cured my HIV AIDS last 3 weeks. I was in a great pain so I told one of my best friends; he told me that there is a great spell caster that can cure my VIRUS. I asked her if she had his email, she gave me his email, I emailed him he talked to me and he perform the necessary rituals and he told me that after two weeks I should go for a test. Which I did, when the doctor told me that am now a HIV negative I couldn’t believe myself I went to see another doctor the result was still the same, I was human on planet earth, so I emailed him and thanked him. Please if you are having a similar problem please visit him/contact him at,
    Dr.Okpokospellhome@gmail.com; all thanks to Dr Okpoko regards..

  9. I want to say hello to the world at large, I am very grateful for the good deeds DR. Henry did for me, I was a HIV patient, everything went bad for me, I couldn’t do things with my friends anymore, I loosed my job, I loosed everything, I was even waiting for death itself, I went searching on the internet I saw many testimonies on how different spell casters helped people in curing their deadly diseases, I collected one spell caster’s email, which DR. Henry I emailed him and he answered me, I told him all problems, he ask me not to worry, that I will be free from the deadly disease, which I did, he casted the spell, and told me that he will send a holy water to me through courier services, I was surprised, because he did not mention it to me before, I paid for the courier delivery service, I got a holy water, he asked me to drink it which I did and he asked me to go for a medical check-up in a hospital, I went to the hospital I went for a HIV test, I was tested HIV negative, I was shocked, I asked myself, “is there still good helpers out there”? I promised to share my testimony to the whole world, I’m now free, I have a better job, if you are passing through pains you need help you can share your problems to DR. Henry through agaguspellhome@live.com

  10. Name: Carol Donald
    Country: U.S.A.
    Its a real miracle temple. Wao! Till today i still imagine how
    dr ajagbo helped me cured my hiv/aids. I’m Miss Carol Donald. from Moore-park. before i met this man on the internet, i was very sick, and cannot even eat because of my sickness i was thinking is this going to be over but not knowing that there is a real spell caster that can help me cure my hiv sickness. until i encountered Dr ajagbo, who help me with his miracles medications, and today i am a healthy woman strong and sand than ever before, am no longer a hiv possitive because a test was later conducted after Dr ajagbo has cast at the hiv sickness he is a famous Dr, and he helped me too in getting my husband who divorced me some months back to my life.. Because he went to the hospital for the hiv test with me he realy see it that i was tested negative. I don’t know how best to express my feelings and my appreciations to dr ajagbo for his wonderful work and the miracle worker.. i wanna say thank you FOR YOUR MIRACLES IN MY LIFE. if you need help or you want any help from him, no need to die in silence anymore. why not contact him, and let him help you out..here is his email adress..ajagbospelltemple@gmail.com. And he is also a specialist in all kind of problems.. SUCH AS BRINGING BACK YOUR LOST LOVER. OR YOU NEED A CHILD, he is always there to help you, just the same way he did my own. And if you think you do not believe in miracles, why not give him a trial! Thanks to you dr ajagbo. the miracle worker… Email contact adress:Ajagbospelltemple@gmail.com

  11. I am so happy right now,I can’t say much I was having hiv and I encounter so many spell casters and they all kept deceiving me until one day,when I was going through the internet I came across a spell caster called dr anegbe who told me everything I need to do,he ask for some items which I could not provide,so he told me he is going to help me get the items but I have too come up with the items fee,so I did and he promised me 24hours he will be done with the cast,and can’t say every thing right now am so happy so if you need help too. Contact him on :anegbesolutiontemple@yahoo.com

  12. Hi my name is Mark Parker and i live in California.This is a testimony i want to make.I was an HIV positive for 8 years taking anti retrovirus.As i was reading online some 5 months ago i saw a testimony on cure of HIV.I decided to give a try.Now as am telling you am very negative tested 4 times in 5 months after finishing mu cure.The cure is a pure herbs from Africa shipped to me through DHL. My cure took about 35 to 40 days.Dear brothers and sisters if you are out there,please the cure is out and rush to have yours.If you are interested,email the researcher using hivhealinghome@live.com I will encourage every person who come across this mail to cure yourself if you are positive.

  13. !!! How To Get Your BEST CURE TO YOUR HIV AND AID Immediately !!!

    My names Laura Zamora, I am from florida usa am here to give my testimony about a doctor who help me in my life. I was infected with HIV virus in the year of 2009,i went to many hospitals, churches for cure but there was no solution out, so I was thinking how can I get a solution out so that i cannot loose my life, I lost everything I have my husband run away from me and also took my children along because of my sickness. One day I was in the river side thinking the next step to take if it is to jump into the river so that I can loose my life totally or just think where I can go to get solution. so a lady walk to me telling me why am I so sad and i open up all to him telling her my stories, she told me that she can help me out that?s the reason she normally come here to help people so that they can be cured because she was into this problem before, she introduce me to a doctor how cast spells for people and gave me he number and email so i called him and also email him.so i gather all my faiths and put in all interest to contact him through his Email address at (habelhomecenter@gmail.com) , so after i have mailed him of helping get my disease cured, i respond to me fast as possible that i should not be afraid, that he is a truthful and powerful doctor which i firstly claimed him to be. So after all set has been done, he promise me that i will be healed but on a condition that i provide him some items and obeyed all his oracle said. I did all by accepting his oracle fact and only to see that the following week Dr.Ben mail me on my mail box that my work is successfully done with his powers, i was first shocked and later arise to be the happiest woman on earth after i have concluded my final test on the hospital by my doctor that i am now HIV- Negative. My papers for check are with me and now i am happy and glad for his miraculous help and power.With these i must to everyone who might seek for any help, either for HIV cure or much more to contact him now at these following email now,Email: (habelhomecenter@gmail.com) ” sir thank you so much for your immediate cure of my disease, i must say for curing my disease, i owe you in return. Thanks and be blessed sir. My name is Anabel James from UK and His Email address is: (habelhomecenter@gmail.com) or you can call him via his cell phone number on +2348133873774

    1. HELLO
      How can I explain this to the world that there is a man who can cure HIV/aids I was HIV over since 21year I have being into HIV drug I can’t anymore I decide to look for help then I found this woman post write about this great man Dr aye, telling people about him that this man have cured to HIV I don’t believe that because all I have in mind is HIV had no cure, thank god for my life today am HIV negative through the power of Dr aye, I contacted this man for help because who write about him drop an email of the man I pick the email and emailed him for the cure this man told me what to do about the cure well am from Australia this man cast a curing spell on me and he told me that he will call me after the cure is done truly he did I was cured for 24hpurs spell what a wonderful man this Dr aye, if you need his cured just email him now or .ayespellalter@l.com you can contact his phone number+23490351070

  14. HELLO
    How can I explain this to the world that there is a man who can cure HIV/aids I was HIV over since 21year I have being into HIV drug I can’t anymore I decide to look for help then I found this woman post write about this great man Dr aye, telling people about him that this man have cured to HIV I don’t believe that because all I have in mind is HIV had no cure, thank god for my life today am HIV negative through the power of Dr aye, I contacted this man for help because who write about him drop an email of the man I pick the email and emailed him for the cure this man told me what to do about the cure well am from Australia this man cast a curing spell on me and he told me that he will call me after the cure is done truly he did I was cured for 24hpurs spell what a wonderful man this Dr aye, if you need his cured just email him now or .ayespellalter@l.com you can contact his phone number+23490351070

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  16. *Greetings to the general public, i want to tell about how i was cured of
    HIV/AIDS disease by a Doctor called Dr ogun. I was browsing through the
    Internet searching for remedy on HIV and i saw comment of people talking
    about how Doctor ogun cured them. I Was scared because i never believed in
    the Internet but i was convince to give him a try because i having no hope
    of been cured of HIV/AIDS so i decided to contact him with his email that
    was listed on the comment (eborogun@outlo
    ok.com (call +2339033364038 whatssap

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